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Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/14426

Title: Pharmacology of Perioperative Intraperitoneal and Intravenous Chemotherapy in Patients with Peritoneal Surface Malignancy
Authors: Van der Speeten, Kurt
Stuart, O. Anthony
Sugarbaker, Paul H.
Issue Date: 2012
Publisher: W B SAUNDERS CO-ELSEVIER INC
Citation: SURGICAL ONCOLOGY CLINICS OF NORTH AMERICA, 21 (4), p. 577-597
Abstract: Peritoneal surface malignancy is a common manifestation of intra-abdominal malignancies. Systemic chemotherapy offers no long-term survival and poor quality of life for these patients in their terminal stages of disease. By contrast, cytoreductive surgery combined with perioperative intraperitoneal and intravenous chemotherapy has resulted in encouraging clinical results. Further improvements should come from both clinical phase II/III studies and pharmacologic research. This article reviews the current pharmacologic data and controversies regarding the perioperative intraperitoneal and intravenous application of chemotherapy.
Notes: [Van der Speeten, Kurt] Ziekenhuis Oost Limburg, Dept Surg Oncol, B-3600 Genk, Belgium. [Van der Speeten, Kurt] Univ Hasselt, Res Grp Oncol, Dept Med, Hasselt, Belgium. [Stuart, O. Anthony; Sugarbaker, Paul H.] Washington Hosp Ctr, Washington Canc Inst, Dept Surg Oncol, Washington, DC 20010 USA.
URI: http://hdl.handle.net/1942/14426
DOI: 10.1016/j.soc.2012.07.013
ISI #: 000310403300007
ISSN: 1055-3207
Category: A1
Type: Journal Contribution
Validation: ecoom, 2013
Appears in Collections: Physiology

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