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Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/13708

Title: Venous Pulse Transit Time in Normal Pregnancy and Preeclampsia
Authors: Tomsin, Kathleen
Mesens, Tinne
Molenberghs, Geert
Gyselaers, Wilfried
Issue Date: 2012
Publisher: SAGE PUBLICATIONS INC
Citation: REPRODUCTIVE SCIENCES, 19 (4), p. 431-436
Abstract: Uncomplicated pregnancies (n = 16) were evaluated longitudinally and compared to early-(n = 12) and late-onset (n = 14) preeclampsia patients, assessed once at diagnosis. Pulse transit time (PTT), equivalent to pulse wave velocity, was measured as the time interval between corresponding characteristics of electrocardiography and Doppler waves, corrected for heart rate, at the level of renal interlobar veins, hepatic veins, and arcuate branches of uterine arteries. Impedance cardiography was used to measure PTT at the level of the thoracic aorta. In normal pregnancy, all PTT increased gradually (P <= .01). Pulse transit time was shorter in late-onset preeclampsia (P < .05) and also in early-onset preeclampsia, with exception for hepatic veins and thoracic aorta (P > .05). Our results indicate that PTT is an easy and highly accessible measure for vascular reactivity at both arterial and venous sites of the circulation. Our observations correlate well with known gestational cardiovascular adaptation mechanisms. This suggests that PTT could be used as a new parameter in the evaluation and prediction of preeclampsia.
Notes: [Tomsin, Kathleen; Mesens, Tinne; Gyselaers, Wilfried] Ziekenhuis Oost Limburg, Dept Obstet & Gynaecol, B-3600 Genk, Belgium. [Tomsin, Kathleen; Gyselaers, Wilfried] Hasselt Univ, Dept Physiol, Diepenbeek, Belgium. [Molenberghs, Geert] Hasselt Univ, I BioStat, Diepenbeek, Belgium. [Molenberghs, Geert] Catholic Univ Louvain, I BioStat, B-3000 Louvain, Belgium.
URI: http://hdl.handle.net/1942/13708
DOI: 10.1177/1933719111424440
ISI #: 000302991400011
ISSN: 1933-7191
Category: A1
Type: Journal Contribution
Validation: ecoom, 2013
Appears in Collections: Centre for Statistics
Biomedical Research Institute
Physiology
Research Institute Center for Statistics

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